Powers, T. (2022) The origin story of rapamycin: systemic bias in biomedical research and cold war politics. Mol. Biol. Cell 33 (13) doi: 10.1091/mbc.E22-08-0377.

Tsverov, J, Yegorov, K, and Powers, T. (2022) Identification of defined structural elements in TOR2 kinase required for TORC2 assembly and function in S. cerevisiae. Mol. Biol. Cell 33 (5) mbcE21120611. doi: 10.1091/mbc.E21-12-0611.

Hill, A., Niles, B., Cuyegkeng, A., and Powers, T. (2018) Redesigning TOR kinase to explore the structural basis for TORC1 and TORC2 assembly. Biomolecules, Jun 1;8(2). pii: E36. doi: 10.3390/biom8020036.

Aouacheria, A. et. al. (2018) Comment on “Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death”. Science June 22; 360(6395)  pii: eaar6910. doi: 10.1126/science.aar6910.

Carmona-Gutierrez, D. et. al. (2018) Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell 5, 4-31.

Vlahakis, A., Muniozguren, N., and Powers, T. (2017) Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy. Autophagy 13, 1804-1812.

Murley, A., Yamada, J., Niles, B.J., Toulmay, A., Prinz, W.A., Powers, T., and Nunnari, J. (2017) Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling. J. Cell Biol. 216, 2679-2689.

Vlahakis, A., Lopez Muniozguren, N., and Powers, T. (2017) Mitochondrial respiration links TOR Complex 2 signaling to calcium regulation and autophagy. Autophagy 13, 1256-1257.

Stauffer, B. and Powers, T. (2017) Target of rapamycin signaling mediates vacuolar fragmentation. Current Genetics 63, 35-42.

Vlahakis, A., Lopez Muniozguren, N., and Powers, T. (2016) Calcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy. J. Cell Biol. 215, 779-788.

Klionsky, D., et. al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1554-8627.

Stauffer, B. and Powers, T. (2015) Target of rapamycin signaling mediates vacuolar fission caused by endoplasmic reticulum stress in S. cerevisiae. Mol. Bio. Cell 26, 4618-4630.

Fresques, T., Niles, B., Aronova, S., Mogri, H., Rakhshandehroo, T., and Powers, T. (2015) Regulation of ceramide synthase by casein kinase 2-dependent phosphorylation in S. cerevisiae.  J. Biol. Chem. 290, 1395-1403.

Vlahakis, A. and Powers, T. (2014) A role for TOR complex 2 in promoting autophagy. Autophagy 10, 2085-2086.

Niles, B.J. and Powers, T. (2014) TOR Complex 2-Ypk1 signaling regulates actin polarization via reactive oxygen species (ROS). Mol. Biol. Cell 25, 3962-3972.

Vlahakis, A., Graef, M., Nunnari, J., and Powers, T. (2014) TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy. Proc Natl Acad Sci USA 111, 10586-10591.

Niles, B.J., Joslin, A.C., Fresques, T., and Powers, T. (2014) TOR Complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation. Cell Reports, 6, 541-552.

Niles, B.J. & Powers, T. (2012) Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae. Cell Cycle 11, 3745-3749

Niles, B.J., Mogri, H., Hill, A., Vlahakis, A., and Powers, T. (2012) Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2. Proc. Natl Acad Sci USA 109, 1536-1541

Liu, Q, Ren, T, Fresques, T, Oppliger, W, Niles, BJ, Hur, W, Sabatini, DM, Hall, MN, Powers, T, Gray, NS. (2012) Selective ATP-Competitive Inhibitors of TOR Suppress Rapamycin-Insensitive Function of TORC2 in Saccharomyces cerevisiae. ACS chemical biology, 7(6): 982-7.

Powers, T., Arovona, S, and Niles, B. (2010) TORC2 and sphingolipid biosynthesis: Lessons from budding yeast. The Enzymes, Vol. XXVII, 177-197.

Powers, T. (2008) Cell growth control: mTOR takes on fat. Mol. Cell 31, 775-776

Aronova, S., Wedaman, K., Aronov, P.A., Fontes, K., Ramos, K., Hammock, B.D., and Powers, T. (2008) Regulation of ceramide biosynthesis by TOR Complex 2. Cell Metabolism 7, 148-158.

Powers, T. (2007) TOR Signaling and S6 Kinase 1: Yeast Catches Up. Cell Metabolism 6, 1-2.

Aronova, S., Wedaman, K.P., Anderson, S., Yates, J. III, and Powers, T. (2007) Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in S. cerevisae. Mol. Biol. Cell 18, 2779-2794.

Martin, D.E., Powers, T., and Hall, M.N. (2006) Regulation of ribosome biogenesis; Where is TOR? Cell Metabolism 4, 259-260.

Reinke, A., Chen, J.C.-Y., Aronova, S., and Powers, T. (2006) Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p. J. Biol. Chem. 281, 31616-31626.

Chen, C.-Y. & Powers, T. (2006) Coordinate regulation of multiple and distinct biosynthetic pathways by TOR and PKA kinases in S. cerevisiae. Current Genetics 49, 281-293

Dilova, I. & Powers, T. (2006) Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae. FEMS Yeast Research Jan 6(1):112-9.

Powers, T. (2004) Ribosome biogenesis: Giant steps for a giant problem. Cell 119, 901-902.

Powers T, Dilova I, Chen CY, Wedaman K (2004) Yeast TOR signaling: a mechanism for metabolic regulation. Curr Top Microbiol Immunol. 279, 39-51

Powers, T., Chen, C.-Y., Dilova, D., Reinke, A., and Wedaman, K.P. (2004) Tor-signaling and Tor-interacting proteins in yeast. Topics in Current Genetics 7, 201-223.

Dilova, I., Aronova, S., Chen, J. C.-Y., and Powers, T. (2004) Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1p/Rtg3p-dependent genes. J. Biol. Chem 279, 46527-46535.

Reinke A, Anderson S, McCaffery JM, Yates J 3rd, Aronova S, Chu S, Fairclough S, Iverson C, Wedaman KP, Powers T. (2004) TOR complex 1 (TORC1) includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in S. cerevisiae. J. Biol. Chem 279, 14752-14672

Wedaman, K.P., Reinke, A., Anderson, S., Yates, J. III, McCaffery, J.M., and Powers, T. (2003) The Tor kinases are in distinct membrane associated protein complexes in S. cerevisiae. Mol. Biol. Cell 14, 1204-1220

Crespo, J.L., Powers, T., Fowler, B., and Hall, M.N. (2002) The TOR controlled transcription activators GLN3, RTG1 and RTG3 are regulated in response to intracellular levels of glutamine. Proc. Natl. Acad. Sci. USA 99, 6784-6789.

Dilova, I., Chen, C.-Y., and Powers, T. (2002). Mks1 in concert with TOR signaling negatively regulates RTG target gene expression in S. cerevisiae. Curr. Biol. 12, 389-395.

Komeili, A., Wedaman, K. P., O’Shea, E. K., and Powers, T. (2000). Mechanism of metabolic control: target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J. Cell Biol. 151, 863-878.

Powers, T. and Walter, P. (1999) Regulation of ribosome biogenesis by the rapamycin-sensitive TOR signaling pathway in Saccharomyces cerevisiae. Mol. Biol. Cell 10, 987-1000.

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Additional Publications by Ted Powers:

Noller, H.F., Stern, S., Moazed, D., Powers, T., Svensson, P., and Changchien, L.M. (1987) Studies on the architecture and function of 16S rRNA. Cold Spring Harbor Symposia on Quantitative Biology 52, 695-708.

Powers, T., Changchien, L.M., Craven, G.R., and Noller, H.F. (1988) Probing the assembly of the 3′ major domain of 16S ribosomal RNA: quaternary interactions involving ribosomal proteins S7, S9, and S19. J. Mol. Biol. 200, 309-319.

Stern, S., Powers, T., Changchien, L.M., and Noller, H.F. (1988) Interaction of ribosomal proteins S5, S6, S11, S12, S18 and S21 with 16S rRNA. J. Mol. Biol. 201, 683-695.

Powers, T., Stern, S., Changchien, L.M., and Noller, H.F. (1988) Probing the assembly of the 3′ major domain of 16S ribosomal RNA: interactions involving ribosomal proteins S2, S3, S10, S13 and S14. J. Mol. Biol. 201, 697-716.

Stern, S., Powers, T., Changchien, L.M., and Noller, H.F. (1989) RNA-protein interactions in 30S ribosomal subunits: folding and function of 16S rRNA. Science 244, 783-790.

Douthwaite, S., Powers, T., Lee, J.Y., and Noller, H.F. (1989) Defining the structural requirements for a helix in 23S ribosomal RNA that confers erthyromycin resistance. J. Mol. Biol. 209, 655-665.

Powers, T. and Noller, H.F. (1990) Dominant lethal mutations in a conserved loop in 16S rRNA. Proc. Natl. Acad. Sci. USA 87, 1042-1046.

Noller, H.F., Moazed, D., Stern, S., Powers, T., Allen, P.N., Robertson, J.M., Weiser, B., and Triman, K. (1990) Structure of rRNA and its functional interactions in translation . In: The Ribosome: Structure, Functions, and Evolution (Eds., Hill, W.E., Dahlberg, A., Garrett, R.A., Moore, P.B., Schlessinger, D., and Warner, J.R.), American Society for Microbiology, Washington, D.C., pp. 73-92.

Powers, T. and Noller, H.F. (1991) A functional pseudoknot in 16S ribosomal RNA. EMBO J. 10, 2203-2214.

Aagaard, C., Rosendahl, G., Dam, M., Powers, T., and Douthwaite, S. (1991) Specific structural probing of plasmid-coded ribosomal RNAs from Escherichia coli. Biochimie 73, 1439-1444.

Noller, H.F., Powers, T., Allen, P.N., Moazed, D., and Stern, S. (1992) rRNA and translation. In: Structural Tools for the Analysis of Protein-Nucleic Acid Complexes (Eds., Lilley,D.M.J., Heumann, H., and Suck, D.), Birkhauser Verlag, Basel, pp. 313-322.

Powers, T. and Noller, H.F. (1993) Evidence for functional interaction between elongation factor Tu and 16S ribosomal RNA. Proc. Natl. Acad. Sci. USA 90, 1364-1368.

Powers, T. and Noller, H.F. (1993) Allele-specific structure probing of plasmid-derived 16S ribosomal RNA from Escherichia coli. Gene 123, 75-80.

Powers, T., Daubresse, G., and Noller, H.F. (1993) Dynamics of in vitro assembly of 16S rRNA into 30S ribosomal subunits. J. Mol. Biol. 232, 362-374.

Powers, T. and Noller, H.F. (1994) Selective perturbation of G530 of 16S rRNA by translational miscoding agents and a streptomycin-dependence mutation in protein S12. J. Mol. Biol. 235, 156-172.

Powers, T. and Noller, H.F. (1994) The 530 loop of 16S rRNA: a signal to EF-Tu? Trends in Genetics 10, 27-31.

Powers, T. and Noller, H.F. (1995) A temperature-dependent conformational rearrangement in the ribosomal protein S4-16S rRNA complex. J. Biol. Chem. 270, 1238-1242.

Powers, T. and Noller, H.F. (1995) Hydroxyl radical footprinting of ribosomal proteins on 16S rRNA. RNA 1, 194-209.

Powers, T. and Walter, P. (1995) Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases. Science 269, 1422-1424.

Noller, H.F., Powers, T., Allen, P.N., Moazed, D., and Stern, S. (1996) rRNA and translation: tRNA selection and movement in the ribosome. In: Ribosomal RNA: Structure, Evolution, Processing and Function in Protein Biosynthesis (Eds., Simmermann, R.A. and Dahlberg, A.E. ), Boca Raton, CRC Press, pp. 239-258.

Powers, T. and Walter, P. (1996) The nascent polypeptide associated complex modulates interactions between the signal recognition particle and the ribosome. Current Biology 6, 331-338.

Noller, H.F., Green, R., Heilek, G., Hoffarth, V., Huttenhofer, A., Joseph, S., Lee, I., Lieberman, K., Mankin, A., Merryman, C., Powers, T., Puglisi, E.V., Samaha, R.R., and Weiser, B. (1996) Structure and function of ribosomal RNA. Biochemistry and Cell Biology 73, 997-1009.

Powers, T. and Walter, P. (1996) The ribosome talks back. Nature 381, 191-192.

Powers, T. and Walter, P. (1997) Co-translation protein targeting catalyzed by the Escherichia coli signal recognition particle and its receptor. EMBO J. 16, 4880-4886.

Powers, T. and Walter, P. (1997) A ribosome at the end of the tunnel. Science 278, 2072-2073.

Arvidson, C.G., Powers, T., Walter, P. and So, M. (1999) Neisseria gonorrhoeae PilA is an FtsY homolog. J. Bacteriol. 181, 731-739.